Mild cognitive impairment: Ten years later

Authors

Ronald C. Petersen, Mayo Clinic
Rosebud O. Roberts, Mayo Clinic
David S. Knopman, Mayo Clinic
Bradley F. Boeve, Mayo Clinic
Yonas E. Geda, Mayo ClinicFollow
Robert J. Ivnik, Mayo Clinic
Glenn E. Smith, Mayo Clinic
Clifford R. Jack, Mayo Clinic

Document Type

Article

Abstract

In the past 10 years, there has been a virtual explosion in the literature concerning the construct of mild cognitive impairment. The interest in this topic demonstrates the increasing emphasis on the identification of the earliest features of cognitive disorders such as Alzheimer disease and other dementias. Mild cognitive impairment represents the earliest clinical features of these conditions and, hence, has become a focus of clinical, epidemiologic, neuroimaging, biomarker, neuropathological, disease mechanism, and clinical trials research. This review summarizes the progress that has been made while also recognizing the challenges that remain. ©2009 American Medical Association. All rights reserved.

Publication Date

12-1-2009

Publication Title

Archives of Neurology

ISSN

00039942

Volume

66

Issue

12

First Page

1447

Last Page

1455

PubMed ID

20008648

Digital Object Identifier (DOI)

10.1001/archneurol.2009.266

Recommended Citation

Petersen, Ronald C.; Roberts, Rosebud O.; Knopman, David S.; Boeve, Bradley F.; Geda, Yonas E.; Ivnik, Robert J.; Smith, Glenn E.; and Jack, Clifford R., "Mild cognitive impairment: Ten years later" (2009). Neurology. 480.
https://scholar.barrowneuro.org/neurology/480