Implicit learning of sequential regularities and spatial contexts in corticobasal syndrome
Document Type
Article
Abstract
The present study investigated two forms of implicit learning in patients with corticobasal syndrome (CBS): contextual cueing and sequence learning. The former primarily implicates the medial temporal lobe system, and the latter, fronto-striatal-cerebellar circuits. Results revealed relatively preserved contextual cueing in patients with CBS. By contrast, sequence learning showed impairments, which seemed to reflect inability to execute correct responses in the presence of intact learning of the sequence. These findings provide the first characterization of implicit learning systems in CBS, and show that the two systems are differentially affected in patients with CBS.
Publication Date
6-1-2007
Publication Title
Neurocase
ISSN
13554794
Volume
13
Issue
3
First Page
133
Last Page
143
PubMed ID
17786771
Digital Object Identifier (DOI)
10.1080/13554790701401852
Recommended Citation
Negash, Selam; Boeve, Bradley F.; Geda, Yonas E.; Smith, Glenn E.; Knopman, David S.; Ivnik, Robert J.; Howard, Darlene V.; Howard, James H.; and Petersen, Ronald C., "Implicit learning of sequential regularities and spatial contexts in corticobasal syndrome" (2007). Neurology. 451.
https://scholar.barrowneuro.org/neurology/451