Neuropsychiatric aspects of primary progressive aphasia

Authors

Yasaman Fatemi, Mayo Medical School
Bradley F. Boeve, Mayo Medical School
Joseph Duffy, Mayo Medical School
Ronald C. Petersen, Mayo Medical School
David S. Knopman, Mayo Medical School
Vladimir Cejka, Mayo Medical School
Glenn E. Smith, Mayo Medical School
Yonas E. Geda, Mayo Medical SchoolFollow

Document Type

Article

Abstract

Few studies have reported neuropsychiatric symptoms (NPS) in primary progressive aphasia (PPA), a neurodegenerative disorder that primarily affects the left hemisphere. Depression is associated with left-sided stroke, but it remains unclear whether depression and other NPS are also associated with PPA. The authors compared the frequency of neuropsychiatric symptoms in 55 cases of PPA with 110 cognitively normal persons matched for age, sex, and education. Depression, apathy, agitation, anxiety, appetite change, and irritability are associated with PPA. Hallucinations, delusions, and night-time behavior were not associated with PPA. © 2011 American Psychiatric Association.

Publication Date

1-1-2011

Publication Title

Journal of Neuropsychiatry and Clinical Neurosciences

ISSN

08950172

Volume

23

Issue

2

First Page

168

Last Page

172

PubMed ID

21677245

Digital Object Identifier (DOI)

10.1176/jnp.23.2.jnp168

Recommended Citation

Fatemi, Yasaman; Boeve, Bradley F.; Duffy, Joseph; Petersen, Ronald C.; Knopman, David S.; Cejka, Vladimir; Smith, Glenn E.; and Geda, Yonas E., "Neuropsychiatric aspects of primary progressive aphasia" (2011). Neurology. 421.
https://scholar.barrowneuro.org/neurology/421