Department

Neurosurgery; Neurology

Document Type

Article

Abstract

A large number of studies have demonstrated that structures within the medial temporal lobe, such as the hippocampus, are intimately involved in declarative memory for objects and people. Although these items are abstractions of the visual scene, specific visual details can change the speed and accuracy of their recall. By recording from 415 neurons in the hippocampus and amygdala of human epilepsy patients as they viewed images drawn from 10 image categories, we showed that the firing rates of 8% of these neurons encode image illuminance and contrast, low-level properties not directly pertinent to task performance, whereas in 7% of the neurons, firing rates encode the category of the item depicted in the image, a high-level property pertinent to the task. This simultaneous representation of high- and low-level image properties within the same brain areas may serve to bind separate aspects of visual objects into a coherent percept and allow episodic details of objects to influence mnemonic performance.

Medical Subject Headings

neurology

Publication Date

2011

Publication Title

Journal of Neurophysiology

ISSN

0022-3077

Volume

105

Issue

6

First Page

2874

Last Page

2884

PubMed ID

21471400

Digital Object Identifier (DOI)

10.1152/jn.00977.2010

Share

COinS