Anterior Motor Strip Displacement in a Boy With Right Frontal Gray Matter Heterotopia Undergoing Epilepsy Surgery

Department

neurology

Document Type

Article

Abstract

The case of a 14-year-old boy with behavioral problems and medically refractory epilepsy related to symptomatic gray matter heterotopia in the right frontal lobe is reported. The patient underwent subdural cortical grid placement for seizure localization and functional mapping prior to lesionectomy. On the basis of the patient's MRI scan, it was predicted that the motor cortex was located adjacent to the abnormality, well anterior to its expected location. This prediction was confirmed by stimulation mapping. The patient underwent successful resection of the lesion under the guidance of the cortical map. Postoperatively, his seizures and behavior improved markedly. This case highlights how eloquent cortex can rarely be drawn toward a region of gray matter heterotopia. In addition, he is one of the few reported cases of focal cortical dysplasia resection with resultant improved behavior. These observations of unusual cortical representations have implications in epilepsy surgery planning.

Medical Subject Headings

neurology

Publication Date

2007

Publication Title

Epilepsy and Behavior

ISSN

1525-5050

Volume

11

Issue

2

First Page

241

Last Page

246

Digital Object Identifier (DOI)

10.1016/j.yebeh.2007.05.003

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