Plasma von Willebrand Factor Is Elevated Hyperacutely After Mild Traumatic Brain Injury.

Document Type

Article

Abstract

Each year in the United States, ∼2.7 million persons seek medical attention for traumatic brain injury (TBI), of which ∼85% are characterized as being mild brain injuries. Many different cell types in the brain are affected in these heterogeneous injuries, including neurons, glia, and the brain vasculature. Efforts to identify biomarkers that reflect the injury of these different cell types have been a focus of ongoing investigation. We hypothesized that von Willebrand factor (vWF) is a sensitive biomarker for acute traumatic vascular injury and correlates with symptom severity post-TBI. To address this, blood was collected from professional boxing athletes (

Publication Date

1-1-2023

Publication Title

Neurotrauma Rep

ISSN

2689-288X

Volume

4

Issue

1

First Page

655

Last Page

662

PubMed ID

37908322

Digital Object Identifier (DOI)

10.1089/neur.2023.0044

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