Optic Neuropathy As the Initial Presenting Sign of -methyl-d-aspartate (NMDA) Encephalitis

Authors

Mark Mugavin, Department of Ophthalmology and Visual Sciences, University of Louisville , Louisville, Kentucky, USA.
Brett H. Mueller, Department of Ophthalmology and Visual Sciences, University of Louisville , Louisville, Kentucky, USA.
Masoom Desai, Department of Neurology, University of Louisville , Louisville, Kentucky, USA.
Karl C. Golnik, Department of Ophthalmology, University of Cincinnati , Ohio, USA.

Document Type

Article

Abstract

A 52-year-old woman presented with painless vision loss for 3 months. She was in custody for allegedly robbing a bank and had recently been diagnosed with paranoid schizophrenia. She had 20/100 VA OD, a 2+RAPD, and optic atrophy. Extensive diagnostic workup including MRI, Fluorescein Angiography, Infectious Disease Panel, lumbar puncture, and leptomeningeal biopsy were unrevealing. Vision in her right eye declined to NLP and her left eye declined to 20/200 VA. Anti N-methyl-D-aspartate (NMDA) Autoimmune Encephalitis was diagnosed based on CSF serology and clinical suspicion. Her clinical course improved as she was treated with corticosteroids and rituximab.

Publication Date

4-1-2017

Publication Title

Neuro-ophthalmology (Aeolus Press)

ISSN

0165-8107

Volume

41

Issue

2

First Page

90

Last Page

93

PubMed ID

28348631

Digital Object Identifier (DOI)

10.1080/01658107.2016.1262431

Recommended Citation

Mugavin, Mark; Mueller, Brett H.; Desai, Masoom; and Golnik, Karl C., "Optic Neuropathy As the Initial Presenting Sign of -methyl-d-aspartate (NMDA) Encephalitis" (2017). Neurology. 1608.
https://scholar.barrowneuro.org/neurology/1608