Incidental findings of CSF leakage in patients without spontaneous intracranial hypotension and development of post-dural puncture headache

Document Type

Article

Abstract

OBJECTIVES: To determine if nerve root sleeve diverticula or CSF leakage correlate with post-dural puncture headache (PDPH). METHODS: A total of 781 lumbar and 408 cervical post-myelogram CTs were reviewed using a total diverticulum and leakage (TDL) score: 1, nerve root sleeve diverticulum not beyond the lateral vertebral body; 2, diverticulum beyond the lateral vertebral body; 3, periradicular contrast; 4, epidural contrast medium collection. Two scores at each level (left, right) were added for a total score. Results were correlated with post-procedure follow-up. RESULTS: PDPH occurred in 22 (2.8 %) lumbar and 15 (3.7 %) cervical patients. Iodine concentration was not significantly different in lumbar (P = 0.14) or cervical (P = 0.85) patients with or without PDPH. Total scores correlated with PDPH after lumbar (P < 0.0001) and cervical (P < 0.0001) myelography. PDPH patients were younger (P = 0.002 lumbar, P = 0.0001 cervical) and more were female (P = 0.039 lumbar, P = 0.045 cervical). Using multiple regression, a lumbar epidural contrast collection or cervical diverticulum extending beyond the lateral vertebral body correlated with PDPH (P < 0.0001 and P = 0.03, respectively). CONCLUSIONS: PDPH correlates with a higher TDL score. Lumbar epidural contrast medium collections and cervical diverticula extending beyond the lateral vertebral body margin are associated with PDPH. KEY POINTS: • Elongated cervical nerve root sleeve diverticula are associated with post-dural puncture headaches. • Lumbar epidural contrast medium collections are associated with post-dural puncture headaches. • This information may help assess the risk of post-dural puncture headache.

Medical Subject Headings

Adolescent; Adult; Aged; Aged, 80 and over; Cerebrospinal Fluid (diagnostic imaging); Diverticulum (complications, diagnostic imaging); Female; Humans; Incidental Findings; Male; Middle Aged; Myelography; Patient Selection; Post-Dural Puncture Headache (etiology); Radiculopathy (complications, diagnostic imaging); Retrospective Studies; Spinal Puncture (adverse effects); Tomography, X-Ray Computed; Young Adult

Publication Date

4-1-2014

Publication Title

European radiology

E-ISSN

1432-1084

Volume

24

Issue

4

First Page

827

Last Page

33

PubMed ID

24272226

Digital Object Identifier (DOI)

10.1007/s00330-013-3070-0

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