Cingulate cortex in pre-MCI cognition
Document Type
Article
Abstract
Studies of Alzheimer's disease over the years have focused on the prodromal stage, or mild cognitive impairment (MCI), in order to understand its evolution and to diagnose this pathology early. More recently, research has focused on an even earlier stage (pre-MCI) characterized in particular by a cognitive complaint. The purpose of this chapter is, first, to describe the different concepts defining pre-MCI, which refers to cognitive or memory complaint, and to define this concept based on biologic markers (abnormal proteins and neuroimaging). In the second part of the chapter, we describe the cognitive performance of these subjects (pre-MCI), and, finally, in the third part we describe the correlations linking cognitive performance of pre-MCI subjects to cingulate cortex, cingulate gyrus, and cingulum bundle.
Medical Subject Headings
Alzheimer Disease (physiopathology); Cognitive Dysfunction (physiopathology); Gyrus Cinguli (physiopathology); Humans; Prodromal Symptoms
Publication Date
1-1-2019
Publication Title
Handbook of clinical neurology
ISSN
0072-9752
Volume
166
First Page
281
Last Page
295
PubMed ID
31731916
Digital Object Identifier (DOI)
10.1016/B978-0-444-64196-0.00015-7
Recommended Citation
Sambuchi, Nathalie; Geda, Yonas Endale; and Michel, Bernard François, "Cingulate cortex in pre-MCI cognition" (2019). Neurology. 1222.
https://scholar.barrowneuro.org/neurology/1222