Smoking affects the phenotype of Alzheimer disease
Document Type
Article
Abstract
Because epidemiologic and in vitro evidence conflict, the authors studied the association between smoking and Alzheimer disease (AD) in 46 never, 47 former, and 15 active smokers with AD followed to autopsy. Disease parameters were examined by smoking status and amount smoked in bivariate tests and in multivariate models controlling for age, sex, education, and APOE status. Smoking status was not associated with cognitive or neuropathologic measures. However, active smokers were significantly younger at death and higher levels of smoking were associated with shorter disease duration. Copyright © 2005 by AAN Enterprises, Inc.
Publication Date
4-12-2005
Publication Title
Neurology
ISSN
00283878
Volume
64
Issue
7
First Page
1301
Last Page
1303
PubMed ID
15824373
Digital Object Identifier (DOI)
10.1212/01.WNL.0000156912.54593.65
Recommended Citation
Sabbagh, Marwan N.; Tyas, S. L.; Emery, S. C.; Hansen, L. A.; Alford, M. F.; Reid, R. T.; Tiraboschi, P.; and Thal, L. J., "Smoking affects the phenotype of Alzheimer disease" (2005). Neurology. 1032.
https://scholar.barrowneuro.org/neurology/1032