Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia

Authors

Maria Andersson, Sct. Hans Hospital
Ola Bergendorff, Lunds Universitet
Mogens Nielsen, Sct. Hans Hospital
Olov Sterner, Lunds Universitet
Robin Witt, Sct. Hans Hospital
Jinglu Ai, China Academy of Traditional Chinese MedicineFollow
Aiping Lu, China Academy of Traditional Chinese Medicine
An Min Wang, China Academy of Traditional Chinese Medicine

Document Type

Article

Abstract

S-(4-hydroxybenzyl)glutathione was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata. The affinity (IC value) of the compound is slightly lower compared to glutamate and glutathione. © 1995. 50

Keywords

Gastrodia elata, glutamate receptor, glutathione derivative, kainic acid, Orchidaceae

Publication Date

1-1-1995

Publication Title

Phytochemistry

ISSN

00319422

Volume

38

Issue

4

First Page

835

Last Page

836

PubMed ID

7766386

Digital Object Identifier (DOI)

10.1016/0031-9422(94)00771-K

Recommended Citation

Andersson, Maria; Bergendorff, Ola; Nielsen, Mogens; Sterner, Olov; Witt, Robin; Ai, Jinglu; Lu, Aiping; and Wang, An Min, "Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia" (1995). Translational Neuroscience. 971.
https://scholar.barrowneuro.org/neurobiology/971