The heteroyohimbine mayumbine binds with high affinity to rat brain benzodiazepine receptors in vitro
Mayumbine, a naturally occurring heteroyohimbine, was isolated from Rauwolfia vomitoria extracts and shown to potently (IC = 76 ± 3.5 nM) inhibit the in vitro binding of H-diazepam to the benzodiazepine sites within the rat GABA(A) receptor complex. 50 3
Natural Product Letters
Digital Object Identifier (DOI)
Ai, Jinglu; Dekermendjian, Kim; Nielsen, Mogens; and Witt, Michael Robin, "The heteroyohimbine mayumbine binds with high affinity to rat brain benzodiazepine receptors in vitro" (1997). Neurobiology. 969.