Association Between Biochemical And Physiological Properties In Single Motor Units

Department

neurobiology

Document Type

Article

Abstract

Motor units from the cat tibialis posterior muscle were examined for an association between physiological and biochemical properties. Functionally isolated motor units were categorized on the basis of their physiological properties. This was followed by quantitative microbiochemical analysis of single muscle fibers from each unit, identified in cross sections using the glycogen‐depletion method. The activities of malate dehydrogenase and β;‐hydroxyacyl‐CoA dehydrogenase distinguished between fatigable (type FF) and fatigue‐resistant (types FR and S) units. The activities of both lactate dehydrogenase and adenylokinase were higher in fast‐than in slow‐contracting units. Cluster analyses, based on both physiological and biochemical properties alone, produced groupings identical to types FF, FR, and S. The association between physiological and biochemical properties substantiates the idea that biochemically distinct groups of motor units correspond to physiologically identifiable groups. Copyright © 1988 John Wiley & Sons, Inc.

Publication Date

1-1-1988

Publication Title

Muscle & Nerve

ISSN

0148639X

Volume

11

Issue

3

First Page

245

Last Page

254

Digital Object Identifier (DOI)

10.1002/mus.880110309

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