Observations on choline acetyltransferase containing structures in the CD-1 mouse brain
Document Type
Article
Abstract
Central cholinergic structures within the CD-1 mouse were evaluated by immunohistochemical visualization of choline acetyltransferase (ChAT) using the monoclonal antibody AB8. Rostrally, cholinergic neurons were seen within the neostriatum, medial septal nucleus (Ch1), ventral (Ch2) and horizontal (Ch3) limb nuclei and nucleus basalis-substantia innominata complex (Ch4). Caudally, cholinergic neurons were seen in the cuneiformis-pedunculopontine nuclei (Ch5), lateral dorsal tegmental (Ch6) and parabigeminal (Ch8) nuclei as well as the medial habenular nucleus and cranial motor nuclei. Additional cholinergic perikarya were found in the hippocampus and cerebral cortex. ChAT stained fibers were observed in the cerebral cortex and in many fiber fascicles. © 1988.
Keywords
Choline acetyltransferase, Cholinergic, Immunohistochemistry, Mouse, Nucleus basalis
Publication Date
1-11-1988
Publication Title
Neuroscience Letters
ISSN
03043940
Volume
84
Issue
1
First Page
7
Last Page
12
PubMed ID
3347374
Digital Object Identifier (DOI)
10.1016/0304-3940(88)90328-X
Recommended Citation
Mufson, Elliott J. and Cunningham, Miles G., "Observations on choline acetyltransferase containing structures in the CD-1 mouse brain" (1988). Translational Neuroscience. 1909.
https://scholar.barrowneuro.org/neurobiology/1909