Intracranial stents for treatment of acute ischemic stroke: evolution and current status
Document Type
Article
Abstract
BACKGROUND: Intravascular stents have been applied to treat a variety of pathophysiologic conditions. With advances in stent design and delivery, stenting has become a viable treatment option in neurovascular disease. Recently, intracranial arterial stenting has received increasing interest as a modality to rapidly and effectively recanalize affected vessels in the setting of acute ischemic stroke. METHODS: To examine the potential of stenting procedures for stroke, we compiled and analyzed relevant experimental and clinical studies in the available databases. RESULTS: Our resulting discussion covers the brief history of stents, from their initial inception in the 1960s, to the developments of interventional cardiology, and finally to the treatment of acute occlusions of the neurovasculature. We also detail technological advances that have improved stent delivery to intracranial arteries and review the several clinical studies that feature stenting for the treatment of acute ischemic stroke. CONCLUSION: Numerous clinical studies have revealed that stents are a quick and efficacious endovascular tool for acute ischemic stroke treatment. It appears likely that issues regarding design, safety, and feasibility of stent-based devices will experience further improvement and refinement, and from fruitful criticism of existing technologies and techniques, along with lessons from past mistakes, will arise safer and more effective devices.
Medical Subject Headings
Angioplasty, Balloon; Brain Ischemia (complications, surgery); Cerebral Arteries (surgery); Cerebral Revascularization; Equipment Design; Humans; Stents; Stroke (etiology, surgery)
Publication Date
12-1-2011
Publication Title
World neurosurgery
E-ISSN
1878-8769
Volume
76
Issue
6 Suppl
First Page
S24
Last Page
34
PubMed ID
22182268
Digital Object Identifier (DOI)
10.1016/j.wneu.2011.02.031
Recommended Citation
Ansari, Saeed; McConnell, Douglas J.; Velat, Gregory J.; Waters, Michael F.; Levy, Elad I.; Hoh, Brian L.; and Mocco, J, "Intracranial stents for treatment of acute ischemic stroke: evolution and current status" (2011). Translational Neuroscience. 1325.
https://scholar.barrowneuro.org/neurobiology/1325