Direct thrombectomy using the Penumbra thromboaspiration catheter for the treatment of cerebral venous sinus thrombosis
OBJECTIVE: Cerebral venous sinus thrombosis (CVST) is a rare cause of stroke. A 21 year-old female presented to our institution in a rapidly deteriorating neurological state following failed systemic heparin therapy for treatment of superior sagittal sinus (SSS) thrombosis. METHODS: The patient underwent emergent mechanical thrombectomy of the thrombosed SSS using the 0.054-inch Penumbra catheter. No adjuvant direct pharmacologic and/or mechanical thrombectomy was performed. RESULTS: Successful venous recanalization was achieved using the Penumbra system. The patient improved symptomatically following the intervention, and she made a complete neurological recovery within 30 days. At 6-month follow-up, the patient had returned to work and school and remained neurologically intact. A repeat MRV showed complete sinus recanalization. CONCLUSION: Direct mechanical thrombectomy using the Penumbra system provided rapid sinus recanalization for the treatment of symptomatic cerebral venous sinus thrombosis. This device is a valuable addition to the neurointerventional armamentarium.
Medical Subject Headings
Angiography, Digital Subtraction; Anticoagulants (therapeutic use); Anticonvulsants (therapeutic use); Brain (diagnostic imaging); Catheters; Cerebral Angiography; Female; Humans; Magnetic Resonance Imaging; Paresis (etiology, therapy); Postoperative Complications (drug therapy, etiology); Seizures (drug therapy, etiology); Sinus Thrombosis, Intracranial (surgery); Stroke (etiology, therapy); Suction; Thrombectomy (methods); Tomography, X-Ray Computed; Valproic Acid (therapeutic use); Warfarin (therapeutic use); Young Adult
Digital Object Identifier (DOI)
Velat, Gregory J.; Skowlund, Christopher J.; Waters, Michael F.; Mocco, J; and Hoh, Brian L., "Direct thrombectomy using the Penumbra thromboaspiration catheter for the treatment of cerebral venous sinus thrombosis" (2012). Translational Neuroscience. 1316.