Direct thrombectomy using the Penumbra thromboaspiration catheter for the treatment of cerebral venous sinus thrombosis

Authors

Gregory J. Velat, Department of Neurological Surgery, McKnight Brain Institute, University of Florida, Gainesville, Florida, USA. gregory.velat@neurosurgery.ufl.edu
Christopher J. Skowlund
Michael F. Waters
J Mocco
Brian L. Hoh

Document Type

Article

Abstract

OBJECTIVE: Cerebral venous sinus thrombosis (CVST) is a rare cause of stroke. A 21 year-old female presented to our institution in a rapidly deteriorating neurological state following failed systemic heparin therapy for treatment of superior sagittal sinus (SSS) thrombosis. METHODS: The patient underwent emergent mechanical thrombectomy of the thrombosed SSS using the 0.054-inch Penumbra catheter. No adjuvant direct pharmacologic and/or mechanical thrombectomy was performed. RESULTS: Successful venous recanalization was achieved using the Penumbra system. The patient improved symptomatically following the intervention, and she made a complete neurological recovery within 30 days. At 6-month follow-up, the patient had returned to work and school and remained neurologically intact. A repeat MRV showed complete sinus recanalization. CONCLUSION: Direct mechanical thrombectomy using the Penumbra system provided rapid sinus recanalization for the treatment of symptomatic cerebral venous sinus thrombosis. This device is a valuable addition to the neurointerventional armamentarium.

Medical Subject Headings

Angiography, Digital Subtraction; Anticoagulants (therapeutic use); Anticonvulsants (therapeutic use); Brain (diagnostic imaging); Catheters; Cerebral Angiography; Female; Humans; Magnetic Resonance Imaging; Paresis (etiology, therapy); Postoperative Complications (drug therapy, etiology); Seizures (drug therapy, etiology); Sinus Thrombosis, Intracranial (surgery); Stroke (etiology, therapy); Suction; Thrombectomy (methods); Tomography, X-Ray Computed; Valproic Acid (therapeutic use); Warfarin (therapeutic use); Young Adult

Publication Date

3-1-2012

Publication Title

World neurosurgery

E-ISSN

1878-8769

Volume

77

Issue

3-4

First Page

591.e15

Last Page

8

PubMed ID

22120408

Digital Object Identifier (DOI)

10.1016/j.wneu.2011.02.020

Recommended Citation

Velat, Gregory J.; Skowlund, Christopher J.; Waters, Michael F.; Mocco, J; and Hoh, Brian L., "Direct thrombectomy using the Penumbra thromboaspiration catheter for the treatment of cerebral venous sinus thrombosis" (2012). Translational Neuroscience. 1316.
https://scholar.barrowneuro.org/neurobiology/1316