Title

SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways

Document Type

Article

Abstract

SIGNIFICANCE: Superoxide dismutase (SOD) enzymes are indispensable and ubiquitous antioxidant defenses maintaining the steady-state levels of O2·(-); no wonder, thus, that their mimics are remarkably efficacious in essentially any animal model of oxidative stress injuries thus far explored.

Publication Date

5-20-2014

Publication Title

Antioxidants & redox signaling

E-ISSN

15577716

Volume

20

Issue

15

First Page

2372

Last Page

2415

PubMed ID

23875805

Digital Object Identifier (DOI)

10.1089/ars.2012.5147

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