ALSUntangled No. 7: Investigating hyperimmune goat serum (Aimspro) for ALS.

Document Type

Article

Abstract

The mechanism of Aimspro remains unproven; if it is an immunomodulator and/or a modulator of sodium channels, it theoretically could be useful in ALS. A single, detailed but significantly flawed case report documents slowing in decline of certain respiratory functions in a patient claiming to have ALS, who started Aimspro shortly after bipap. Based upon this limited information, ALSUntangled supports further study of Aimspro, either in ALS animal models or in a small phase 2 trial with clear and objective endpoints carried out by skilled trialists familiar with the problems inherent with ALS clinical studies. Until a trial is undertaken, however, we do not support further use of this product by PALS.

Keywords

Amyotrophic Lateral Sclerosis, Animals, Clinical Trials as Topic, Goats, Humans, Internet, Serum

Medical Subject Headings

Amyotrophic Lateral Sclerosis; Animals; Clinical Trials as Topic; Goats; Humans; Internet; Serum

Publication Date

12-1-2010

Publication Title

Amyotroph Lateral Scler

ISSN

1471-180X

Volume

11

Issue

6

First Page

571

Last Page

573

PubMed ID

21077806

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