Prophylactic sternal plating with pectoralis advancement flaps after sternotomy in patients with a history of chest irradiation

Document Type

Article

Abstract

Deep sternal infections secondary to bony instability and malunion, can result in mediastinitis. Previous authors have described the use of prophylactic rigid plate fixation in high-risk patients. The purpose of our study is to review the use of prophylactic sternal platting with pectoralis advancement flaps in high-risk patients with a history of chest irradiation. Fourteen patients (July 2003-September 2008) with a history of chest irradiation who underwent a median sternotomy followed by prophylactic rigid plate fixation of the sternum were reviewed. Breast cancer was the most common etiology of chest irradiation (n=11, 78%). The average EuroSCORE was 24.06% with 72% of patients having a preoperative New York Heart Association (NYHA) class≥III. There were no episodes of sternal non-union, mediastinitis or death. Follow-up was 100% with a 0% 30-day and a 7.1% one-year mortality rate (non-cardiac). A comparison between mean preoperative left ventricular ejection fraction (LVEF) (49.6%) and postoperative LVEF (59.7%) was statistically significant (P<0.0001). All living patients currently maintain a NYHA class I/II. Prophylactic rigid plate fixation and pectoralis flap coverage decreases the risk of developing sternal dehiscence and postoperative wound complications and should therefore be considered in high-risk patients with a history of chest irradiation.

Medical Subject Headings

Aged; Bone Plates; Cardiac Surgical Procedures; Female; Humans; Male; Mediastinitis (etiology, prevention & control); Michigan; Pectoralis Muscles (surgery); Radiotherapy (adverse effects); Sternotomy (adverse effects, instrumentation, mortality); Surgical Flaps (adverse effects); Surgical Wound Dehiscence (etiology, prevention & control); Surgical Wound Infection (etiology, prevention & control); Thoracic Cavity (radiation effects); Time Factors; Treatment Outcome; Wound Closure Techniques (adverse effects, instrumentation, mortality)

Publication Date

3-1-2011

Publication Title

Interactive cardiovascular and thoracic surgery

E-ISSN

1569-9285

Volume

12

Issue

3

First Page

355

Last Page

8

PubMed ID

21138917

Digital Object Identifier (DOI)

10.1510/icvts.2010.247262

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