Natural Killer-Like T-Cell Lymphoma: A Rare Cause of Acute Liver Failure

Authors

Ishani Shah, Department of Internal Medicine, St. Joseph's Hospital and Medical Center, Phoenix, AZ.
Neil Vyas, Department of Gastroenterology, St. Joseph's Hospital and Medical Center, Phoenix, AZ.
Justin A. Reynolds, Department of Transplant Hepatology, St. Joseph's Hospital and Medical Center, Phoenix, AZ.

Document Type

Article

Abstract

Acute liver failure is characterized by encephalopathy and disruption of hepatic function, often requiring liver transplantation to prevent fatal consequences. We present a 33-year-old man with recurrent lymphoma presenting with acute liver failure, which was initially thought to be from drug-induced liver injury associated with his chemotherapy medication, asparaginase. However, liver biopsy revealed malignant infiltration by lymphoma. The subtype of lymphoma was natural killer-like T-cell lymphoma, which is an uncommon variant, and has rarely been associated with hepatic infiltration. His condition rapidly worsened with development of multiorgan failure leading to death.

Publication Date

7-1-2019

Publication Title

ACG case reports journal

ISSN

2326-3253

Volume

6

Issue

7

First Page

e00145

PubMed ID

31620542

Digital Object Identifier (DOI)

10.14309/crj.0000000000000145

Recommended Citation

Shah, Ishani; Vyas, Neil; and Reynolds, Justin A., "Natural Killer-Like T-Cell Lymphoma: A Rare Cause of Acute Liver Failure" (2019). SJHMC Faculty. 3.
https://scholar.barrowneuro.org/sjhmc/3