Neuropsychological outcomes after psychosocial intervention for depression in Parkinson's disease.

Document Type

Article

Abstract

The authors describe neuropsychological outcomes in people with Parkinson's disease (PD) after their participation in an NIH-sponsored, randomized, controlled trial of cognitive-behavioral treatment for depression. Improvements in mood were associated with modest gains in verbal memory and executive functioning over the 10-week treatment period and accounted for greater variance in neuropsychological outcomes at the end of treatment than other known correlates of cognitive functioning in PD, such as disease severity, age, and education. Baseline working memory and executive skills were also associated with depression improvement over time.

Medical Subject Headings

Adult; Aged; Aged, 80 and over; Cognitive Behavioral Therapy; Depression; Executive Function; Female; Humans; Male; Memory, Short-Term; Middle Aged; Models, Statistical; Neuropsychological Tests; Outcome Assessment, Health Care; Parkinson Disease; Psychiatric Status Rating Scales; Severity of Illness Index

Publication Date

1-1-2014

Publication Title

The Journal of neuropsychiatry and clinical neurosciences

ISSN

1545-7222

Volume

26

Issue

1

First Page

57

Last Page

63

PubMed ID

24275895

Digital Object Identifier (DOI)

10.1176/appi.neuropsych.12120381

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