Neurologic recovery after therapeutic hypothermia in patients with post-cardiac arrest myoclonus

Authors

Jason M. Lucas, Beth Israel Deaconess Medical Center
Michael N. Cocchi, Beth Israel Deaconess Medical Center
Justin Salciccioli, Beth Israel Deaconess Medical Center
Jessica A. Stanbridge, Beth Israel Deaconess Medical Center
Romergryko G. Geocadin, The Johns Hopkins Hospital
Susan T. Herman, Beth Israel Deaconess Medical CenterFollow
Michael W. Donnino, Beth Israel Deaconess Medical Center

Document Type

Article

Abstract

Early myoclonus in comatose survivors of cardiac arrest, even when it is not myoclonic status epilepticus (MSE), is considered a sign of severe global brain ischemia and has been associated with high rates of mortality and poor neurologic outcomes. We report on three survivors of primary circulatory cardiac arrests who had good neurologic outcomes (two patients with a CPC score=1 and one patient with a CPC score=2) after mild therapeutic hypothermia, despite exhibiting massive myoclonus within the first 4. h after return of spontaneous circulation. The concept that early myoclonus heralds a uniformly poor prognosis may need to be reconsidered in the era of post-cardiac arrest mild therapeutic hypothermia. © 2011 Elsevier Ireland Ltd.

Publication Date

2-1-2012

Publication Title

Resuscitation

ISSN

03009572

E-ISSN

18731570

Volume

83

Issue

2

First Page

265

Last Page

269

PubMed ID

21963817

Digital Object Identifier (DOI)

10.1016/j.resuscitation.2011.09.017

Recommended Citation

Lucas, Jason M.; Cocchi, Michael N.; Salciccioli, Justin; Stanbridge, Jessica A.; Geocadin, Romergryko G.; Herman, Susan T.; and Donnino, Michael W., "Neurologic recovery after therapeutic hypothermia in patients with post-cardiac arrest myoclonus" (2012). Neurology. 548.
https://scholar.barrowneuro.org/neurology/548