Title

Post-Streptococcal Vasculopathy With Evolution to Degos' Disease

Department

neurology

Document Type

Article

Abstract

Degos' disease or malignant atrophic papulosis is a rare disseminated occlusive vasculopathy affecting the skin, gastrointestinal tract, central nervous system, and less often other organ systems. The exact etiology of this vasculopathy has not been established. Infections, autoimmune disease and coagulation defects have been proposed as underlying pathogenic mechanisms, but none have been confirmed. Here, we report the clinical, radiological and histopathologic features of Degos' disease in a 41-year-old man following streptococcal throat infection. Prior postulated hypothesis as post-infectious immunologic mechanism may be further supported by this case. © 2010 Elsevier B.V.

Medical Subject Headings

neurology

Publication Date

2011

Publication Title

Journal of the Neurological Sciences

ISSN

0022510X

Volume

300

Issue

43467

First Page

157

Last Page

159

Digital Object Identifier (DOI)

10.1016/j.jns.2010.10.007

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