Title

Vertical and Radial Attentional Neglect in Corticobasal Syndrome

Document Type

Article

Abstract

Corticobasal degeneration (CBD), a tau-related neurodegenerative disease, is characterized by limb rigidity, dystonia, myoclonus, apraxia, and cognitive deficits. We report a patient with probable corticobasal syndrome, a major phenotype of CBD, who revealed both lower vertical and proximal radial attentional neglect on line bisection tests. Brain imaging revealed bilateral parietal atrophy with hypometabolism in the bilateral parietal, dorsolateral prefrontal, and premotor cortices. Bilateral impairment in the dorsal attentional network reduces the allocation of spatial attention to lower and proximal space, causing lower vertical and proximal radial attentional neglect. Screening for various types of spatial neglect may be important in tailoring management and rehabilitation strategies for patients with CBD.

Medical Subject Headings

Attention (physiology); Basal Ganglia Diseases (diagnosis, pathology); Brain (pathology); Humans; Male; Middle Aged; Neurodegenerative Diseases (diagnosis, pathology); Orientation, Spatial (physiology)

Publication Date

9-1-2019

Publication Title

Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology

E-ISSN

1543-3641

Volume

32

Issue

3

First Page

208

Last Page

213

PubMed ID

31517705

Digital Object Identifier (DOI)

10.1097/WNN.0000000000000204

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