Vertical and Radial Attentional Neglect in Corticobasal Syndrome
Corticobasal degeneration (CBD), a tau-related neurodegenerative disease, is characterized by limb rigidity, dystonia, myoclonus, apraxia, and cognitive deficits. We report a patient with probable corticobasal syndrome, a major phenotype of CBD, who revealed both lower vertical and proximal radial attentional neglect on line bisection tests. Brain imaging revealed bilateral parietal atrophy with hypometabolism in the bilateral parietal, dorsolateral prefrontal, and premotor cortices. Bilateral impairment in the dorsal attentional network reduces the allocation of spatial attention to lower and proximal space, causing lower vertical and proximal radial attentional neglect. Screening for various types of spatial neglect may be important in tailoring management and rehabilitation strategies for patients with CBD.
Medical Subject Headings
Attention (physiology); Basal Ganglia Diseases (diagnosis, pathology); Brain (pathology); Humans; Male; Middle Aged; Neurodegenerative Diseases (diagnosis, pathology); Orientation, Spatial (physiology)
Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology
Digital Object Identifier (DOI)
Julayanont, Parunyou; Burks, David W.; and Heilman, Kenneth M., "Vertical and Radial Attentional Neglect in Corticobasal Syndrome" (2019). Neurology. 1250.