Title

Should the guidelines for monitoring serum cholesterol levels in the elderly be re-evaluated?

Document Type

Article

Abstract

Elevated circulating cholesterol can have profound effects on the health of an individual. Such excess cholesterol can promote coronary artery disease, production and accumulation of β-amyloid in the brain, and possibly Alzheimer's disease (AD). In a clinical trial evaluating the benefit of a cholesterol-lowering drug in the treatment of AD, mean cholesterol levels at baseline among individuals participating in the trial were found to be relatively high. Based on this observation we suggest that cholesterol levels should be actively monitored in the elderly, as many individuals with AD are over 65 years of age and therefore excluded by currently accepted guidelines.

Publication Date

1-1-2002

Publication Title

Journal of Molecular Neuroscience

ISSN

08958696

Volume

19

Issue

1-2

First Page

209

Last Page

212

PubMed ID

12212783

Digital Object Identifier (DOI)

10.1007/s12031-002-0035-1

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