Title

Implications of Oligomeric Amyloid-Beta (oAβ

Department

Neurobiology

Document Type

Article

Abstract

Neuronal and network-level hyperexcitability is commonly associated with increased levels of amyloid-β (Aβ) and contribute to cognitive deficits associated with Alzheimer's disease (AD). However, the mechanistic complexity underlying the selective loss of basal forebrain cholinergic neurons (BFCNs), a well-recognized characteristic of AD, remains poorly understood. In this study, we tested the hypothesis that the oligomeric form of amyloid-β (oAβ

Publication Date

1-20-2021

Publication Title

The Journal of neuroscience : the official journal of the Society for Neuroscience

ISSN

1529-2401

Volume

41

Issue

3

First Page

555

Last Page

575

PubMed ID

33239400

Digital Object Identifier (DOI)

10.1523/JNEUROSCI.0876-20.2020

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