Resorbable polylactide implants for cervical graft containment in an ovine spinal fusion model
The safety and efficacy of a resorbable plate and screw implant system for preventing the dislocation of autologous tricortical iliac crest graft material in a cervical spine model without additional metallic fixation were evaluated. The resorbable polymer implants were fabricated using an amorphous copolymer, sterilized by e-beam irradiation. A total of 13 adult, female ewes were used in the study. A total of 58 radiographs of the implants were evaluated over 12 month survival period. No displacement of the graft material and implant failure were observed. Biomechanical evaluation demonstrated a significant reduction in motion in all three planes of motion at the survival periods.
Transactions - 7th World Biomaterials Congress
Cornwall, G. B.; Ames, C. P.; Crawford, N. R.; Chamberlain, R. H.; Seim, H. S.; and Turner, A. S., "Resorbable polylactide implants for cervical graft containment in an ovine spinal fusion model" (2004). Neurobiology. 837.