Title

Tissue sodium accumulation and peripheral insulin sensitivity in maintenance hemodialysis patients.

Document Type

Article

Abstract

BACKGROUND: Recent data suggest that sodium (Na

METHODS: Eleven MHD patients and eight controls underwent hyperinsulinemic-euglycemic-euaminoacidemic clamp studies to measure glucose (GDR) and leucine disposal rates (LDR), as well as lower left leg

RESULTS: The median GDR and LDR levels were lower, and the median muscle Na

CONCLUSIONS: These data suggest that excessive muscle Na

Keywords

Adult, Biomarkers, Blood Glucose, Body Composition, Female, Glucose, Humans, Insulin, Insulin Resistance, Leucine, Magnetic Resonance Imaging, Male, Middle Aged, Muscle, Skeletal, Organ Specificity, Renal Dialysis, Skin, Sodium

Medical Subject Headings

Adult; Biomarkers; Blood Glucose; Body Composition; Female; Glucose; Humans; Insulin; Insulin Resistance; Leucine; Magnetic Resonance Imaging; Male; Middle Aged; Muscle, Skeletal; Organ Specificity; Renal Dialysis; Skin; Sodium

Publication Date

6-1-2017

Publication Title

J Cachexia Sarcopenia Muscle

ISSN

2190-6009

Volume

8

Issue

3

First Page

500

Last Page

507

PubMed ID

28150400

Digital Object Identifier (DOI)

10.1002/jcsm.12179

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