Tissue sodium accumulation and peripheral insulin sensitivity in maintenance hemodialysis patients.
BACKGROUND: Recent data suggest that sodium (Na
METHODS: Eleven MHD patients and eight controls underwent hyperinsulinemic-euglycemic-euaminoacidemic clamp studies to measure glucose (GDR) and leucine disposal rates (LDR), as well as lower left leg
RESULTS: The median GDR and LDR levels were lower, and the median muscle Na
CONCLUSIONS: These data suggest that excessive muscle Na
Adult, Biomarkers, Blood Glucose, Body Composition, Female, Glucose, Humans, Insulin, Insulin Resistance, Leucine, Magnetic Resonance Imaging, Male, Middle Aged, Muscle, Skeletal, Organ Specificity, Renal Dialysis, Skin, Sodium
Medical Subject Headings
Adult; Biomarkers; Blood Glucose; Body Composition; Female; Glucose; Humans; Insulin; Insulin Resistance; Leucine; Magnetic Resonance Imaging; Male; Middle Aged; Muscle, Skeletal; Organ Specificity; Renal Dialysis; Skin; Sodium
J Cachexia Sarcopenia Muscle
Digital Object Identifier (DOI)
Deger, Serpil Muge; Wang, Ping; Fissell, Rachel; Ellis, Charles D; Booker, Cindy; Sha, Feng; Morse, Jennifer L; Stewart, Thomas G; Gore, John C; Siew, Edward D; Titze, Jens; and Ikizler, Talat Alp, "Tissue sodium accumulation and peripheral insulin sensitivity in maintenance hemodialysis patients." (2017). Translational Neuroscience. 1555.