Sex differences in sodium deposition in human muscle and skin.
The aim of this work was to investigate possible sex differences in the patterns of sodium deposition between muscle and skin using sodium MRI. A total of 38 subjects were examined for comparisons: 20 males, aged 25-79years with a median age of 51; 18 females, aged 38-66years, median age 53. All subjects underwent sodium MRI scans of the calf muscles together with cross sections through four calibration standards containing known sodium contents (10mM, 20mM, 30mM, and 40mM). Tissue sodium concentrations (TSC) in muscle and skin were then calculated by comparing signal intensities between tissues and reference standards using a linear analysis. A Wilcoxon rank sum test was applied to the ΔTSC (=TSC
Adult, Aged, Body Mass Index, Female, Humans, Linear Models, Magnetic Resonance Imaging, Male, Middle Aged, Muscle, Skeletal, Sex Factors, Skin, Sodium
Medical Subject Headings
Adult; Aged; Body Mass Index; Female; Humans; Linear Models; Magnetic Resonance Imaging; Male; Middle Aged; Muscle, Skeletal; Sex Factors; Skin; Sodium
Magnetic resonance imaging
Digital Object Identifier (DOI)
Wang, Ping; Deger, Muge Serpil; Kang, Hakmook; Ikizler, T Alp; Titze, Jens; and Gore, John C, "Sex differences in sodium deposition in human muscle and skin." (2017). Translational Neuroscience. 1547.