Title

A new approach towards predictability of epileptic seizures: KLT dimension

Document Type

Article

Abstract

This paper proposes a measure of complexity of the epileptic electroencephalogram (EEG) based on the dimensionality of the Karhunen-Loeve Transform (KLT) in the time domain. We estimate the KLT dimensionality by assuming the same observation noise level in the EEG during the interictal period (between the seizures) as the one during an epileptic seizure (ictal period). Utilizing an optimality criterion based on the T-index [1] and the predictability time, derived from the created KLT dimensionality profiles, we show that 10 out of 15 seizures in one patient with temporal lobe epilepsy were predictable with an average predictability time of about 36 minutes.

Medical Subject Headings

Algorithms; Brain (physiopathology); Brain Mapping (methods); Cerebral Cortex (physiopathology); Electroencephalography (methods); Epilepsy (diagnosis, physiopathology); Hippocampus (physiopathology); Humans; Linear Models; Models, Neurological; Monitoring, Ambulatory (methods); Quality Control; Reproducibility of Results; Sensitivity and Specificity

Publication Date

1-1-2003

Publication Title

Biomedical sciences instrumentation

ISSN

0067-8856

Volume

39

First Page

123

Last Page

8

PubMed ID

12724880

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