Evaluating the sinus and Nasal Quality of Life Survey in the pediatric cystic fibrosis patient population

Authors

Deborah X. Xie, Vanderbilt University School of Medicine, Nashville, TN, USA; Surgical Outcomes Center for Kids, Vanderbilt University, Nashville, TN, USA.
Jeffanie Wu, Surgical Outcomes Center for Kids, Vanderbilt University, Nashville, TN, USA; Vanderbilt University, Nashville, TN, USA.
Katherine Kelly, Vanderbilt University School of Medicine, Nashville, TN, USA; Surgical Outcomes Center for Kids, Vanderbilt University, Nashville, TN, USA.
Rebekah F. Brown, Surgical Outcomes Center for Kids, Vanderbilt University, Nashville, TN, USA; Department of Pediatrics, Division of Pulmonary Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Chevis Shannon, Surgical Outcomes Center for Kids, Vanderbilt University, Nashville, TN, USA; Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Frank W. Virgin, Surgical Outcomes Center for Kids, Vanderbilt University, Nashville, TN, USA; Department of Otolaryngology-Head & Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: frank.w.virgin@vanderbilt.edu.

Document Type

Article

Abstract

INTRODUCTION: The Sinus and Nasal Quality of Life Survey (SN-5) is a validated quality of life (QOL) questionnaire for chronic rhinosinusitis in patients age 2-12. Its utility in the cystic fibrosis (CF) has been studied, but not yet validated. The purpose of this study is to determine the effectiveness of the SN-5 for evaluation of sinonasal symptoms in the pediatric CF population. METHODS: This retrospective study analyzed SN-5 surveys completed between 2012 and 2015 by pediatric CF patients and caregivers. Baseline and follow-up overall QOL scores and specific symptom scores were obtained from surveys completed in the three-year span. Non-parametric statistics were conducted to identify differences in survey data. RESULTS: A total of 165 patients completed baseline and follow-up surveys. The overall QOL of the patient cohort did not change over the duration of the study (p = 0.660). Thirty-seven patients indicated higher overall QOL, with all five symptom scores showing significant improvement. Analysis by age group showed that QOL was significantly correlated with all five symptoms for children ages 0-4. In patients 5-12 years, overall QOL was only correlated with sinus infection (r = -0.3090, p = 0.01). QOL was significantly correlated with sinus infection (r = -0.2903, p = 0.04) and allergy symptoms (r = -0.5644, p < 0.01) in patients >12 years of age. CONCLUSION: There remains a need for a validated CRS QOL tool for children with CF. Though the SN-5 has previously been described as a potential instrument, our data suggest that it may be more valuable in children ages 0-4.

Medical Subject Headings

Adolescent; Child; Child, Preschool; Cystic Fibrosis (complications); Female; Follow-Up Studies; Humans; Infant; Male; Paranasal Sinuses; Quality of Life; Retrospective Studies; Rhinitis (epidemiology, etiology); Severity of Illness Index; Sinusitis (epidemiology, etiology); Surveys and Questionnaires

Publication Date

11-1-2017

Publication Title

International journal of pediatric otorhinolaryngology

E-ISSN

1872-8464

Volume

102

First Page

133

Last Page

137

PubMed ID

29106860

Digital Object Identifier (DOI)

10.1016/j.ijporl.2017.09.014

Recommended Citation

Xie, Deborah X.; Wu, Jeffanie; Kelly, Katherine; Brown, Rebekah F.; Shannon, Chevis; and Virgin, Frank W., "Evaluating the sinus and Nasal Quality of Life Survey in the pediatric cystic fibrosis patient population" (2017). ENT and Skull Base Surgery. 33.
https://scholar.barrowneuro.org/ent-and-skull-base-surgery/33