Effects of depression and Parkinson's disease on cognitive functioning
This study compared the performance of Parkinson's disease (PD) patients with and without depression, patients with depression alone, and normal control subjects on a cognitive screening instrument, the Mattis Dementia Rating Scale (DRS) to evaluate the influences of depression and Parkinson's disease on cognition. PD affects overall level of cognitive functioning and, to a lesser extent, DRS Initiation/Perseveration, Construction, and Attention. Diminished memory was primarily related to depression. Treatment of depression may ameliorate aspects of cognitive dysfunction in the PD patient with depression.
Medical Subject Headings
Aged; Antidepressive Agents (therapeutic use); Antiparkinson Agents (therapeutic use); Attention (physiology); Cognition (physiology); Dementia (psychology); Depressive Disorder (drug therapy, psychology); Female; Humans; Male; Memory (physiology); Middle Aged; Neuropsychological Tests; Parkinson Disease (drug therapy, psychology); Psychiatric Status Rating Scales
The Journal of neuropsychiatry and clinical neurosciences
Digital Object Identifier (DOI)
Norman, Suzanne; Tröster, Alexander I.; Fields, Julie A.; and Brooks, Rebecca, "Effects of depression and Parkinson's disease on cognitive functioning" (2002). Clinical Neuropsychology. 70.