Title

Effects of depression and Parkinson's disease on cognitive functioning

Document Type

Article

Abstract

This study compared the performance of Parkinson's disease (PD) patients with and without depression, patients with depression alone, and normal control subjects on a cognitive screening instrument, the Mattis Dementia Rating Scale (DRS) to evaluate the influences of depression and Parkinson's disease on cognition. PD affects overall level of cognitive functioning and, to a lesser extent, DRS Initiation/Perseveration, Construction, and Attention. Diminished memory was primarily related to depression. Treatment of depression may ameliorate aspects of cognitive dysfunction in the PD patient with depression.

Medical Subject Headings

Aged; Antidepressive Agents (therapeutic use); Antiparkinson Agents (therapeutic use); Attention (physiology); Cognition (physiology); Dementia (psychology); Depressive Disorder (drug therapy, psychology); Female; Humans; Male; Memory (physiology); Middle Aged; Neuropsychological Tests; Parkinson Disease (drug therapy, psychology); Psychiatric Status Rating Scales

Publication Date

1-1-2002

Publication Title

The Journal of neuropsychiatry and clinical neurosciences

ISSN

0895-0172

Volume

14

Issue

1

First Page

31

Last Page

6

PubMed ID

11884652

Digital Object Identifier (DOI)

10.1176/jnp.14.1.31

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