Neuropsychological functioning of recidivist alcoholics treated with disulfiram: A follow-up report

Document Type

Article

Abstract

Does disulfiram have a deleterious effect on neuropsychological functions? Neuropsychological test performance of 15 chronic alcoholics before and after being placed on disulfiram was compared with a similar group of 9 milieu-treated alcoholics also tested twice. Results indicated that (1) both groups showed a high incidence of significant neuropsychological impairment prior to either disulfiram or milieu treatment; (2) on second testing, both groups showed improved neuropsychological test performance. Disulfiram-treated alcoholics generally did not show increased neuropsychological impairment after being maintained on low dosages of this drug for 2 weeks. Certain results, however, suggest that the effect of disulfiram on short-term memory should be investigated. © 1980 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

Publication Date

1-1-1980

Publication Title

Substance Use and Misuse

ISSN

10826084

Volume

15

Issue

2

First Page

287

Last Page

294

PubMed ID

7399760

Digital Object Identifier (DOI)

10.3109/10826088009040016

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