Pharmacologic and Cell-Based Therapies for Acute Spinal Cord Injury

Authors

Nikolay L. Martirosyan, Department of Neurosurgery, Allen Memorial Hospital, UnityPoint Clinic, 146 W Dale Street Suite 201, Waterloo, IA 50703, USA. Electronic address: Nikolay.Martirosyan@unitypoint.org.Follow

Document Type

Article

Abstract

This article provides a review of current pharmacologic and cell-based modalities used for the management of acute spinal cord injury (SCI). The literature search was focused on clinical trials performed in the United States and Canada. Despite the significant advance in research, there is no definitive treatment option for SCI. Instead, existing pharmacologic and cell-based modalities provide only minimal neurologic recovery benefits. This can be attributed to the complex pathophysiology of SCI and spinal cord regeneration. Further research is imperative to better understand these mechanisms and discover definitive treatment modalities.

Medical Subject Headings

Clinical Trials as Topic; Humans; Spinal Cord; Spinal Cord Injuries (drug therapy)

Publication Date

7-1-2021

Publication Title

Neurosurgery clinics of North America

E-ISSN

1558-1349

Volume

32

Issue

3

First Page

389

Last Page

395

PubMed ID

34053726

Digital Object Identifier (DOI)

10.1016/j.nec.2021.03.010

Recommended Citation

Martirosyan, Nikolay L., "Pharmacologic and Cell-Based Therapies for Acute Spinal Cord Injury" (2021). Neurosurgery. 1712.
https://scholar.barrowneuro.org/neurosurgery/1712